Symbol
Name
ID

Relb
avian reticuloendotheliosis viral (v-rel) oncogene related B
MGI:103289

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Neutrophilia	Impaired lymphocyte transformation with phytohemagglutinin
Disease(s) Associated with RELB	Neutrophilia	Impaired lymphocyte transformation with phytohemagglutinin
immunodeficiency 53

Mouse Phenotypes

decreased B cell proliferation

impaired neutrophil phagocytosis

thymus atrophy

thymus hypoplasia

increased spleen weight

spleen hyperplasia

abnormal definitive hematopoiesis

abnormal erythropoiesis

myeloid hyperplasia

extramedullary hematopoiesis

anemia

increased bone marrow cell number

increased eosinophil cell number

abnormal proerythroblast morphology

decreased dendritic cell number

decreased T cell number

abnormal gamma-delta T cell morphology

increased spleen red pulp amount

decreased spleen white pulp amount

abnormal immunoglobulin level

increased IgE level

increased IgM level

abnormal cytotoxic T cell physiology

abnormal macrophage physiology

Availability

Mouse Genotype

Relb^shep/Relb^shep

Relb^tm1Brv/Relb^tm1Brv

Relb^tm1.1Fwei/Relb^tm1.1Fwei
Tg(Lck-cre)I57Jxm/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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